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Dima Biotech

SKU(재고 관리 코드):PME100915

Human BRD4 Protein, hFc Tag

Human BRD4 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CAP;HUNK1;HUNKI;MCAP

DESCRIPTION

Recombinant human BRD4 protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

O60885

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

BRD4(Met1-Phe1362) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 178.4 kDa after removal of the signal peptide.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

USAGE

Research use only

IMAGES

sp-PME100915 BRD4 hFc PAGE 300

Figure 1. Human BRD4 Protein, hFc Tag on SDS-PAGE under reducing condition.

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