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Dima Biotech

SKU(재고 관리 코드):PME100962

Human IFNGR2 Protein, hFc Tag

Human IFNGR2 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

IFN-gamma-R2;IFN-gamma-R-beta;AF-1

DESCRIPTION

Recombinant human IFNGR2 protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

P38484

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

IFNGR2(Ser28-Gln247) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 51.0 kDa after removal of the signal peptide. The apparent molecular mass of IFNGR2-hFc is approximately 55-70 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]

USAGE

Research use only

IMAGES

sp-PME100962 IFNGR2 hFc PAGE 300

Figure 1. Human IFNGR2 Protein, hFc Tag on SDS-PAGE under reducing condition.

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