| TARGET | |
|---|---|
| SYNONYMS |
Tyrosine-protein kinase Mer;Proto-oncogene c-Mer;Receptor tyrosine kinase MerTK |
| DESCRIPTION |
Recombinant human MERTK protein with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q12866 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
MERTK(Ala21-Ile505) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 78.8 kDa after removal of the signal peptide. The apparent molecular mass of MERTK-hFc is approximately 100-130 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100977
Human MERTK Protein, hFc Tag
Human MERTK Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human MERTK Protein, hFc Tag on SDS-PAGE under reducing condition.
