| TARGET | |
|---|---|
| SYNONYMS |
B7-H5;B7H5;C10orf54;DD1alpha;Dies1;GI24;PD-1H;PP2135;SISP1;VISTA |
| DESCRIPTION |
Recombinant Human B7-H5 with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9H7M9 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
B7-H5(Phe33-Ala194) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of B7-H5-hFc is approximately 55-70 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Immunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation (PubMed:20666777).[UniProtKB/Swiss-Prot Function] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME101041
Human B7-H5 Protein, hFc Tag
Human B7-H5 Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human B7-H5 Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human B7-H5 Protein, hFc Tag (PME101041) can bind Anti-B7-H5 Neutralizing antibody (BME100109) in a linear range of 2.44–625.00 ng/mL.
