TARGET | |
---|---|
SYNONYMS |
Delta1;DLK;DLK-1;FA1;pG2;Pref-1;PREF1;ZOG |
DESCRIPTION |
Recombinant human DLK1 protein with C-terminal human Fc tag |
DELIVERY |
Under development |
UNIPROT ID |
P80370 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
DLK1 (Ala24-Gln303) hFc(Glu99-ALA330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 56.32 kDa after removal of the signal peptide. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME101059