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Dima Biotech

PME101066

Human ULBP2 Protein, hFc Tag

Human ULBP2 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

ALCAN-alpha;N2DL2;NKG2DL2;RAET1H;RAET1L
DESCRIPTION

Recombinant human ULBP2 protein with C-terminal human Fc tag
DELIVERY

Under development
UNIPROT ID

Q9BZM5
EXPRESSION HOST

HEK293
TAG

C-Human Fc Tag
MOLECULAR CHARACTERIZATION

ULBP2 (Gly26-Ser216) hFc(Glu99-ALA330)
MOLECULAR WEIGHT

The protein has a predicted molecular mass of 46.53 kDa after removal of the signal peptide.
PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
USAGE

Research use only
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