| TARGET | |
|---|---|
| SYNONYMS |
IL21;a11;nterleukin-21 |
| DESCRIPTION |
Recombinant Human IL21 with C-terminal Human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9HBE4 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
IL21(Gln30-Ser162) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide.The apparent molecular mass of IL21-hFc is approximately 35-55 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME101088
Human IL21 Protein, hFc Tag
Human IL21 Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human IL21 Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human IL21R, His tagged protein (PME100587) can bind Human IL21, hFc Tagged protein (PME101088) in a linear range of 1.6-40 ng/ml.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human IL21 Protein, hFc Tag (PME101088) can bind Anti-IL21 Neutralizing antibody (BME100103) in a linear range of 2.44–156.25 ng/mL.
