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Dima Biotech

PME101097

Human CD11 Protein, hFc Tag

Human CD11 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CD11A;LFA-1;LFA1A
DESCRIPTION

Recombinant human CD11 protein with C-terminal human Fc tag
DELIVERY

Under development
UNIPROT ID

P20701
EXPRESSION HOST

HEK293
TAG

C-Human Fc Tag
MOLECULAR CHARACTERIZATION

CD11 (Pro26-Leu1090) hFc(Glu99-ALA330)
MOLECULAR WEIGHT

The protein has a predicted molecular mass of 142.67 kDa after removal of the signal peptide.
PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
BACKGROUND

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
USAGE

Research use only
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