| TARGET | |
|---|---|
| SYNONYMS |
ACE-2;CEH;CE2 |
| DESCRIPTION |
Recombinant Human ACE2 Protein with N-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q9BYF1 |
| EXPRESSION HOST |
HEK293 |
| TAG |
N-6×His Tag |
| MOLECULAR CHARACTERIZATION |
6×His ACE2(Gln18-Ser740) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 84.4 kDa after removal of the signal peptide. The apparent molecular mass of His-ACE2 is approximately 100-130 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100490
Human ACE2 Protein, His Tag
Human ACE2 Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1. Human ACE2 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human ACE2, His Tagged protein（PME100490）can bind S-RBD, hFc tagged protein (PME100487) in a linear range of 0.128-80.0 ng/ml.
