TARGET | |
---|---|
SYNONYMS |
C7orf15;CD112R |
DESCRIPTION |
Recombinant human PVRIG protein with C-terminal human Fc tag |
DELIVERY |
In Stock |
UNIPROT ID |
Q6DKI7 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
PVRIG(Met1-Thr25 Pro80-Ala170) hFc(Glu99-Ala330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 38.2 kDa after removal of the signal peptide.The apparent molecular mass of PVRIG-hFc is approximately 55-70 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME100090
Human PVRIG Protein, hFc Tag
Human PVRIG Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human PVRIG Protein, hFc Tag on SDS-PAGE under reducing condition.