| TARGET | |
|---|---|
| SYNONYMS |
AXL;FO |
| DESCRIPTION |
Recombinant Human AXL with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P30530 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
AXL(Ala26-Pro449) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 71.9 kDa after removal of the signal peptide.The apparent molecular mass of AXL-hFc is approximately 100-130 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100532
Human AXL Protein, hFc Tag
Human AXL Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human AXL Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human AXL, hFc tagged protein (PME100532) can bind Anti-AXL Neutralizing Antibody (BME100033) in a linear range of 0.64-80.0 ng/ml.
