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Dima Biotech

SKU(재고 관리 코드):PME100549

Human AMHR2 Protein, hFc Tag

Human AMHR2 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

AMHR;MISR2;MISRII;MRII

DESCRIPTION

Recombinant Human AMHR2 Protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

Q16671

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

AMHR2 (Pro18-Leu149) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 40.3 kDa after removal of the signal peptide.The apparent molecular mass of AMHR2-hFc is approximately 55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.

USAGE

Research use only

IMAGES

sp-PME100549 AMHR2 hFc PAGE 300

Figure 1. Human AMHR2 Protein, hFc Tag on SDS-PAGE under reducing condition.

elisa-PME100549 AMHR2 hFc ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human AMHR2 Protein, hFc Tag (PME100549) can bind A

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