TARGET | |
---|---|
SYNONYMS |
IL-11 R alpha;L-11 RA;L11RA;nterleukin-11 receptor subunit alpha;L-11 receptor subunit alpha;L-11R subunit alpha;L-11R-alpha |
DESCRIPTION |
Recombinant Human IL11RA with C-terminal human Fc tag |
DELIVERY |
In Stock |
UNIPROT ID |
Q14626 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
IL11RA(Ser24-Ala370) hFc(Glu99-Ala330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL11RA-hFc is approximately 35-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME100578
Human IL11RA Protein, hFc Tag
Human IL11RA Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human IL11RA Protein, hFc Tag on SDS-PAGE under reducing condition.