TARGET | |
---|---|
SYNONYMS |
Ep;EPR;ER |
DESCRIPTION |
Recombinant Human EREG with C-terminal human Fc tag |
DELIVERY |
In Stock |
UNIPROT ID |
O14944 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
EREG(Val63-Leu108) hFc(Glu99-Ala330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of EREG-hFc is approximately 35-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME100617
Human EREG Protein, hFc Tag
Human EREG Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human EREG Protein, hFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human EREG Protein, hFc Tag (PME100617) can bind Anti-EREG antibody(DMC424), IgG1 Chimeric mAb in a linear range of 0.64–16 ng/mL.