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Dima Biotech

SKU(재고 관리 코드):PME-M100013

Mouse Trop2 Protein, hFc Tag

Mouse Trop2 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
Target

Synonyms

Tpm-2;Trop-2

Description

Recombinant mouse Trop2 protein with C-terminal human Fc tag

Delivery

In Stock

Uniprot ID

Q8BGV3

Expression Host

HEK293

Tag

C-Human Fc Tag

Molecular Characterization

Mouse Trop2(Gln25-Gly270) hFc(Glu99-Ala330)

Molecular Weight

The protein has a predicted molecular mass of 54.1 kDa after removal of the signal peptide.The apparent molecular mass of mTrop2-hFc is approximately 55-70 kDa due to glycosylation.

Purity

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation & Reconstitution

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage & Shipping

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Background

This gene belongs to the tropomyosin family which encodes proteins that bind to actin filaments and stabilize them by regulating access to actin modifying proteins. The encoded protein is a high molecular weight tropomyosin expressed in slow skeletal muscle. In humans, mutations in this gene are associated with nemaline myopathy, cap disease and distal arthrogryposis syndromes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]

Usage

Research use only

IMAGES

sp-PME M100013 Trop2 hFc PAGE 300

Figure 1. Mouse Trop2 Protein, hFc Tag on SDS-PAGE under reducing condition.

elisa-PME M100013 Mouse Trop2 hFc ELISA Fig2

Figure 2. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Mouse Trop2 Protein, hFc Tag (PME-M100013) can bind anti-Trop2 monoclonal antibody (DME100075) in a linear range of 0.64-80 ng/mL.

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