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Dima Biotech

SKU(재고 관리 코드):PME100743

Human CD63 Protein, hFc Tag

Human CD63 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CD63 antigen;ranulophysin;AMP-3;imp1;elanoma-associated antigen ME491;MA81H;cular melanoma-associated antigen;etraspanin-30;Tspan-30

DESCRIPTION

Recombinant human CD63 protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

P08962

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

CD63(Ala103-Val203) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 37.7 kDa after removal of the signal peptide. The apparent molecular mass of CD63-hFc is approximately 35-55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]

USAGE

Research use only

IMAGES

sp-PME100743 CD63 hFc PAGE 300

Figure 1. Human CD63 Protein, hFc Tag on SDS-PAGE under reducing condition.

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