TARGET | |
---|---|
SYNONYMS |
Prolactin receptor;PRL-R |
DESCRIPTION |
Recombinant human PRLR protein with C-terminal human Fc tag |
DELIVERY |
In Stock |
UNIPROT ID |
P16471 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
PRLR(Gln25-Asp234) hFc(Glu99-Ala330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of PRLR-hFc is approximately 55-70 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME100750
Human PRLR Protein, hFc Tag
Human PRLR Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human PRLR Protein, hFc Tag on SDS-PAGE under reducing condition.