제품 정보로 건너뛰기
1 1

Dima Biotech

SKU(재고 관리 코드):PME100750

Human PRLR Protein, hFc Tag

Human PRLR Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

Prolactin receptor;PRL-R

DESCRIPTION

Recombinant human PRLR protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

P16471

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

PRLR(Gln25-Asp234) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 50.5 kDa after removal of the signal peptide. The apparent molecular mass of PRLR-hFc is approximately 55-70 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

USAGE

Research use only

IMAGES

sp-PME100750 PRLR hFc PAGE 300

Figure 1. Human PRLR Protein, hFc Tag on SDS-PAGE under reducing condition.

전체 세부 정보 보기