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Dima Biotech

SKU(재고 관리 코드):PME100756

Human CLEC4C Protein, hFc Tag

Human CLEC4C Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

BDCA-2;CD303

DESCRIPTION

Recombinant human CLEC4C protein with N-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

Q8WTT0

EXPRESSION HOST

HEK293

TAG

N-Human Fc Tag

MOLECULAR CHARACTERIZATION

hFc(Glu99-Ala330) CLEC4C(Asn45-Ile213)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 46.1 kDa after removal of the signal peptide. The apparent molecular mass of hFc-CLEC4C is approximately 55-70 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

USAGE

Research use only

IMAGES

sp-PME100756 CLEC4C hFc PAGE 300

Figure 1. Human CLEC4C Protein, hFc Tag on SDS-PAGE under reducing condition.

elisa-PME100756 hFc CLEC4C ELISA Fig2

Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CLEC4C Protein, hFc Tag (PME100756) can bind Anti-CLEC4C (litifilimab biosimilar) mAb (BME100155) in a linear range of 0.64–80.00 ng/mL.

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