TARGET | |
---|---|
SYNONYMS |
Cannabinoid receptor 1;CB-R;Cnr1 |
DESCRIPTION |
Recombinant mouse CB1 protein with C-terminal human Fc tag |
DELIVERY |
In Stock |
UNIPROT ID |
P47746 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
Mouse CB1(Met1-Leu118) hFc(Glu99-Ala330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 39.4 kDa after removal of the signal peptide. The apparent molecular mass of mCB1-hFc is approximately 40-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME-M100055
Mouse CB1 Protein, hFc Tag
Mouse CB1 Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Mouse CB1 Protein, hFc Tag on SDS-PAGE under reducing condition.