| TARGET | |
|---|---|
| SYNONYMS |
B4;CVID3;MGC12802 |
| DESCRIPTION |
Recombinant human CD19 protein with C-terminal mouse Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P15391 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Mouse Fc Tag |
| MOLECULAR CHARACTERIZATION |
CD19(Pro20-Lys291) mFc(Pro99-Lys330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 56.3 kDa after removal of the signal peptide. The apparent molecular mass of CD19-mFc is approximately 70-100 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME100781
Human CD19 Protein, mFc Tag
Human CD19 Protein, mFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human CD19 Protein, mFc Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CD19 Protein, mFc Tag (PME100781) can bind Anti-CD19 (inebilizumab biosimilar) mAb (BME100051) in a linear range of 0.64–16 ng/mL.
