TARGET | |
---|---|
SYNONYMS |
U-PAR;uPAR;CD87 |
DESCRIPTION |
Recombinant human PLAUR protein with C-terminal 6×His tag |
DELIVERY |
In Stock |
UNIPROT ID |
Q03405 |
EXPRESSION HOST |
HEK293 |
TAG |
C-6×His Tag |
MOLECULAR CHARACTERIZATION |
PLAUR(Leu23-Arg303) 6×His tag |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of PLAUR-His is approximately 35-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME100791
Human PLAUR Protein, His Tag
Human PLAUR Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1. Human PLAUR Protein, His Tag on SDS-PAGE under reducing condition. |