TARGET | |
---|---|
SYNONYMS |
CC-CKR-6;CKR-L3;DRY6;GPRCY4;CD196 |
DESCRIPTION |
Recombinant human CCR6 protein with C-terminal mouse Fc tag |
DELIVERY |
In Stock |
UNIPROT ID |
P51684 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Mouse Fc Tag |
MOLECULAR CHARACTERIZATION |
CCR6(Met1-Leu47) mFc(Pro99-Lys330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 31.7 kDa after removal of the signal peptide. The apparent molecular mass of CCR6-mFc is approximately 35-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME101105
Human CCR6 Protein, mFc Tag
Human CCR6 Protein, mFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human CCR6 Protein, mFc Tag on SDS-PAGE under reducing condition.