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Dima Biotech

SKU(재고 관리 코드):PME101136

Human PYY Protein, hFc Tag

Human PYY Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

PYY-I;PYY1

DESCRIPTION

Recombinant Human PYY with N-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

P10082

EXPRESSION HOST

HEK293

TAG

N-Human Fc Tag

MOLECULAR CHARACTERIZATION

hFc(Glu99-Ala330) PYY(Tyr29-Tyr64)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 30.5 kDa after removal of the signal peptide.The apparent molecular mass of hFc-PYY is approximately 35-55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]

USAGE

Research use only

IMAGES

sp-PME101136 PYY hFc PAGE 300

Figure 1. Human PYY Protein, hFc Tag on SDS-PAGE under reducing condition.

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