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Dima Biotech

SKU(재고 관리 코드):PME-C100011

Cynomolgus BTN3A1 Protein, His Tag

Cynomolgus BTN3A1 Protein, His Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

Butyrophilin protein

DESCRIPTION

Recombinant Cynomolgus BTN3A1 protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

A0A330KVC6

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

BTN3A1(Gln1-Ser218) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 24.3 kDa after removal of the signal peptide. The apparent molecular mass of cBTN3A1-His is approximately 25-35 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

USAGE

Research use only

IMAGES

sp-PME C100011 BTN3A1 His PAGE 300

Figure 1. Cynomolgus BTN3A1 Protein, His Tag on SDS-PAGE under reducing condition.

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