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Dima Biotech

SKU(재고 관리 코드):PME-M100075

Mouse BMP6 Protein, His Tag

Mouse BMP6 Protein, His Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

BMP-6;VGR-1

DESCRIPTION

Recombinant mouse BMP6 protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

P20722

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

Mouse BMP6(Cys21-His510) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 54.9 kDa after removal of the signal peptide. The apparent molecular mass of mBMP6-His is approximately 35-70 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Mice lacking this gene exhibit delayed ossification of the sternum, iron overload, and reduced fertility in females. [provided by RefSeq, Jul 2016]

USAGE

Research use only

IMAGES

sp-PME M100075 BMP6 His PAGE 300

Figure 1. Mouse BMP6 Protein, His Tag on SDS-PAGE under reducing condition.

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