TARGET | |
---|---|
SYNONYMS |
Granulocyte Colony-Stimulating Factor;G-CSF;Pluripoietin;Filgrastim;Lenograstim;CSF3;C17orf33;GCSF |
DESCRIPTION |
Recombinant Human Granulocyte Colony-Stimulating Factor is produced by our E.coli expression system and the target gene encoding Thr31-Pro204 is expressed. |
DELIVERY |
In Stock |
UNIPROT ID |
P09919 |
EXPRESSION HOST |
E.coli |
TAG | |
MOLECULAR CHARACTERIZATION |
Not available |
MOLECULAR WEIGHT |
18.8 KDa |
PURITY |
Greater than 95% as determined by reducing SDS-PAGE. |
FORMULATION & RECONSTITUTION |
Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.004% Tween 80, 5% Mannitol, pH 4.0. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17. |
USAGE |
Research use only |
SKU(재고 관리 코드):PME30003
Human G-CSF Protein
Human G-CSF Protein
PRODUCT DATA
IMAGES
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.