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Dima Biotech

SKU(재고 관리 코드):PME30006

Human IL-16 Protein

Human IL-16 Protein

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

Pro-Interleukin-16;Interleukin-16;IL-16;Lymphocyte Chemoattractant Factor;LCF;IL16

DESCRIPTION

Recombinant Human Interleukin-16 is produced by our E.coli expression system and the target gene encoding Met1-Ser130 is expressed.

DELIVERY

In Stock

UNIPROT ID

AAC12732.1

EXPRESSION HOST

E.coli

TAG
MOLECULAR CHARACTERIZATION

Not available

MOLECULAR WEIGHT

13.4 KDa

PURITY

Greater than 95% as determined by reducing SDS-PAGE.

FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Interleukin-16 (IL-16) is a CD8 T cell-derived cytokine that induces chemotaxis of CD4 T cells and CD4 monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 T cells. Human and murine IL-16 show significant cross-species reactivity.

USAGE

Research use only

IMAGES

sp-PME30006 C045 AAC12732.1 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

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