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Dima Biotech

SKU(재고 관리 코드):PME30008

Human M-CSF (C-6His) Protein

Human M-CSF (C-6His) Protein

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

Macrophage Colony-Stimulating Factor 1;CSF-1;M-CSF;MCSF;Lanimostim;CSF1

DESCRIPTION

Recombinant Human Macrophage Colony-Stimulating Factor is produced by our Mammalian expression system and the target gene encoding Glu33-Arg255 is expressed with a 6His tag at the C-terminus.

DELIVERY

In Stock

UNIPROT ID

P09603

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

Not available

MOLECULAR WEIGHT

26.17 KDa

PURITY

Greater than 95% as determined by reducing SDS-PAGE.

FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.

USAGE

Research use only

IMAGES

sp-PME30008 C417 P09603 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

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