TARGET | |
---|---|
SYNONYMS |
C-C Motif Chemokine 1;Small-Inducible Cytokine A1;T Lymphocyte-Secreted Protein I-309;CCL1;SCYA1 |
DESCRIPTION |
Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed. |
DELIVERY |
In Stock |
UNIPROT ID |
P22362 |
EXPRESSION HOST |
E.coli |
TAG | |
MOLECULAR CHARACTERIZATION |
Not available |
MOLECULAR WEIGHT |
8.62 KDa |
PURITY |
Greater than 95% as determined by reducing SDS-PAGE. |
FORMULATION & RECONSTITUTION |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection. |
USAGE |
Research use only |
SKU(재고 관리 코드):PME30012
Human CCL1 Protein
Human CCL1 Protein
PRODUCT DATA
IMAGES
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.