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Dima Biotech

SKU(재고 관리 코드):PME30018

Human CCL18 (N-6His) Protein

Human CCL18 (N-6His) Protein

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

C-C Motif Chemokine 18;Alternative Macrophage Activation-Associated CC Chemokine 1;AMAC-1;CC Chemokine PARC;Dendritic Cell Chemokine 1;DC-CK1;Macrophage Inflammatory Protein 4;MIP-4;Pulmonary and Activation-Regulated Chemokine;Small-Inducible Cytokine A18;CCL18;AMAC1;DCCK1;MIP4;PARC;SCYA18

DESCRIPTION

Recombinant Human C-C Motif Chemokine 18 is produced by our E.coli expression system and the target gene encoding Ala21-Ala89 is expressed with a 6His tag at the N-terminus.

DELIVERY

In Stock

UNIPROT ID

P55774

EXPRESSION HOST

E.coli

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

Not available

MOLECULAR WEIGHT

10.1 KDa

PURITY

Greater than 95% as determined by reducing SDS-PAGE.

FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4 and CD8 T-cells and thus may play a role in both humoral and cell-mediated immunity responses.

USAGE

Research use only

IMAGES

sp-PME30018 CF38 P55774 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

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