TARGET | |
---|---|
SYNONYMS |
Fibroblast growth factor 7;FGF-7;Heparin-binding growth factor 7;HBGF-7;Keratinocyte growth factor;FGF7 |
DESCRIPTION |
Recombinant Human Fibroblast Growth Factor 7/Keratinocyte growth factor is produced by our Mammalian expression system and the target gene encoding Cys32-Thr194 is expressed with a 6His tag at the C-terminus. |
DELIVERY |
In Stock |
UNIPROT ID |
P21781 |
EXPRESSION HOST |
HEK293 |
TAG |
C-6×His Tag |
MOLECULAR CHARACTERIZATION |
Not available |
MOLECULAR WEIGHT |
20 KDa |
PURITY |
Greater than 95% as determined by reducing SDS-PAGE. |
FORMULATION & RECONSTITUTION |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation. |
USAGE |
Research use only |
SKU(재고 관리 코드):PME30025
Human KGF (C-6His) Protein
Human KGF (C-6His) Protein
PRODUCT DATA
IMAGES
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
Figure 2. Measured in a cell proliferation assay using HaCaT cells. The ED50 for this effect is 10.94 ng/ml.