| TARGET | |
|---|---|
| SYNONYMS |
UPF0556 protein C19orf10;stromal cell-derived growth factor SF20;C19orf10;Myeloid-derived growth factor;MYDGF |
| DESCRIPTION |
Recombinant Human Myeloid-derived Growth Factor is produced by our E.coli expression system and the target gene encoding Ser33-Leu173 is expressed with a 6His tag at the N-terminus. |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q969H8 |
| EXPRESSION HOST |
E.coli |
| TAG | |
| MOLECULAR CHARACTERIZATION |
Not available |
| MOLECULAR WEIGHT |
18 KDa |
| PURITY |
Greater than 95% as determined by reducing SDS-PAGE. |
| FORMULATION & RECONSTITUTION |
Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen, prostate and lung, and weakly expressed in the left ventricle and liver. Bone marrow-derived monocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-based therapies for ischemic tissue repair. |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME30031
Human MYDGF (N-6His) Protein
Human MYDGF (N-6His) Protein
PRODUCT DATA
IMAGES
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.
