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Dima Biotech

SKU(재고 관리 코드):PME30042

Human ELAPOR1 (C-6His) Protein

Human ELAPOR1 (C-6His) Protein

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

ELAPOR1;ndosome-Lysosome Associated Apoptosis And Autophagy Regulator 1;IG121;IAA1324

DESCRIPTION

Recombinant Human Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 is produced by our Mammalian expression system and the target gene encoding Thr42-Lys910 is expressed with a 6His tag at the C-terminus.

DELIVERY

In Stock

UNIPROT ID

Q6UXG2

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

Not available

MOLECULAR WEIGHT

96.2 KDa

PURITY

Greater than 95% as determined by reducing SDS-PAGE.

FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated with breast and endometrial cancers,but its mechanism of action remains unknown.May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. That EIG121 is a good endometrial biomarker associated with a hyperestrogenic state and estrogen-related type I endometrial adenocarcinoma.

USAGE

Research use only

IMAGES

sp-PME30042 C16P Q6UXG2 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

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