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Dima Biotech

SKU(재고 관리 코드):PME30062

Human IL-3 (N-6His) Protein

Human IL-3 (N-6His) Protein

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

Interleukin-3;IL-3;Hematopoietic Growth Factor;Mast Cell Growth Factor;MCGF;Multipotential Colony-Stimulating Factor;P-Cell-Stimulating Factor;IL3

DESCRIPTION

Recombinant Human Interleukin-3 is produced by our E.coli expression system and the target gene encoding Ala20-Phe152 is expressed with a 6His tag at the N-terminus.

DELIVERY

In Stock

UNIPROT ID

P08700

EXPRESSION HOST

E.coli

TAG
MOLECULAR CHARACTERIZATION

Not available

MOLECULAR WEIGHT

16.6 KDa

PURITY

Greater than 95% as determined by reducing SDS-PAGE.

FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Interleukin-3 (IL-3) is a potent growth promoting cytokine. IL-3 can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. IL-3 exerts its biological function through binding to specific cell surface receptors. The amino acid sequences of this protein among different species share relatively low identity and its activity is highly species-specific. IL-3 has also been shown to possess neurotrophic activity, and is thought to be associated with neurologic disorders.

USAGE

Research use only

IMAGES

sp-PME30062 CF63 P08700 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

elisa-PME30062 CF63 P08700 ELISA 0

Figure 2. Loaded Human IL-3RA-Fc on Protein A Biosensor, can bind Human IL-3 with an affinity constant of 3.89uM as determined in BLI assay.

elisa-PME30062 CF63 P08700 ELISA 1

Figure 3. Loaded Human IL-3RA-Fc-Avi on Protein A Biosensor, can bind Human IL-3 with an affinity constant of 3.74 uM as determined in BLI assay.

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