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Dima Biotech

SKU(재고 관리 코드):PME30075

Human IGFBP-1 (C-6His) Protein

Human IGFBP-1 (C-6His) Protein

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

Insulin-like growth factor-binding protein 1;IBP-1;IGF-binding protein 1;IGFBP-1;Placental protein 12;PP12

DESCRIPTION

Recombinant Human Insulin-like Growth Factor-binding Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala26-Asn259 is expressed with a 6His tag at the C-terminus.

DELIVERY

In Stock

UNIPROT ID

P08833

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

Not available

MOLECULAR WEIGHT

26.1 KDa

PURITY

Greater than 95% as determined by reducing SDS-PAGE.

FORMULATION & RECONSTITUTION

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs).

USAGE

Research use only

IMAGES

sp-PME30075 CU66 P08833 SDS PAGE 0

Figure 1. Greater than 95% as determined by reducing SDS-PAGE.

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