TARGET | |
---|---|
SYNONYMS |
Lymphotoxin-Alpha;LT-Alpha;TNF-Beta;Tumor Necrosis Factor Ligand Superfamily Member 1;LTA;TNFB;TNFSF1 |
DESCRIPTION |
Recombinant Human Tumor Necrosis Factor Beta is produced by our E.coli expression system and the target gene encoding Leu35-Leu205 is expressed. |
DELIVERY |
In Stock |
UNIPROT ID |
P01375 |
EXPRESSION HOST |
E.coli |
TAG | |
MOLECULAR CHARACTERIZATION |
Not available |
MOLECULAR WEIGHT |
18.8 KDa |
PURITY |
Greater than 95% as determined by reducing SDS-PAGE. |
FORMULATION & RECONSTITUTION |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Tumor Necrosis Factor β (TNF-β) is a secreted protein belonging to the tumor necrosis factor family. TNF-β binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM in homotrimeric form, binds to TNFRSF3/LTBR in heterotrimeric form with LTB. TNF-β forms heterotrimers with lymphotoxin-beta, which anchors TNF-β to the cell surface. TNF-β mediates the inflammatory, immunostimulatory, and antiviral response, involves in the formation of second lymphoid organs during development, has a role in apoptosis. TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo. |
USAGE |
Research use only |
SKU(재고 관리 코드):PME30085
Human TNF beta Protein
Human TNF beta Protein
PRODUCT DATA
IMAGES
Figure 1. Greater than 95% as determined by reducing SDS-PAGE.