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Dima Biotech

SKU(재고 관리 코드):PME101175

Human PROKR1 Protein, hFc Tag

Human PROKR1 Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

GPR73;GPR73a;PK-R1;PKR1;ZAQ

DESCRIPTION

Recombinant Human PROKR1 Protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

Q8TCW9

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

PROKR1(Met1-Lys62) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 33.1 kDa after removal of the signal peptide. The apparent molecular mass of PROKR1-hFc is approximately 35-70 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]

USAGE

Research use only

IMAGES

sp-PME101175 PROKR1 hFc PAGE 300

Figure 1. Human PROKR1 Protein, hFc Tag on SDS-PAGE under reducing condition.

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