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Dima Biotech

SKU(재고 관리 코드):PME101184

Human CLDN4(145-157) Protein, mFc Tag

Human CLDN4(145-157) Protein, mFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CPE-R;CPER;CPETR;CPETR1;hCPE-R;WBSCR8

DESCRIPTION

Recombinant human CLDN4(145-157) Protein with C-terminal mouse Fc tag

DELIVERY

In Stock

UNIPROT ID

O14493

EXPRESSION HOST

HEK293

TAG

C-mouse Fc Tag

MOLECULAR CHARACTERIZATION

CLDN4(Gln145-Lys157) mFc(Pro99-Lys330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 27.7 kDa after removal of the signal peptide. The apparent molecular mass of CLDN4(145-157)-mFc is approximately 25-35 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]

USAGE

Research use only

IMAGES

sp-PME101184 CLDN4145 157 mFc PAGE 300

Figure 1. Human CLDN4(145-157) Protein, mFc Tag on SDS-PAGE under reducing condition.

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