TARGET | |
---|---|
SYNONYMS |
AMDM;ANPb;NPR2;ECDM;GC-B;GCB;GUC2B;GUCY2B;NPRB;NPRBi;SNSK |
DESCRIPTION |
Recombinant Human ANPRB Protein with C-terminal 6×His tag |
DELIVERY |
In Stock |
UNIPROT ID |
P20594 |
EXPRESSION HOST |
HEK293 |
TAG |
C-6×His Tag |
MOLECULAR CHARACTERIZATION |
ANPRB(Arg23-Ile458) 6×His tag |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 49.3 kDa after removal of the signal peptide. |
PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME101196
Human ANPRB Protein, His Tag
Human ANPRB Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1. Human ANPRB Protein, His Tag on SDS-PAGE under reducing condition.