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Dima Biotech

SKU(재고 관리 코드):PME101196

Human ANPRB Protein, His Tag

Human ANPRB Protein, His Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

AMDM;ANPb;NPR2;ECDM;GC-B;GCB;GUC2B;GUCY2B;NPRB;NPRBi;SNSK

DESCRIPTION

Recombinant Human ANPRB Protein with C-terminal 6×His tag

DELIVERY

In Stock

UNIPROT ID

P20594

EXPRESSION HOST

HEK293

TAG

C-6×His Tag

MOLECULAR CHARACTERIZATION

ANPRB(Arg23-Ile458) 6×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 49.3 kDa after removal of the signal peptide.

PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]

USAGE

Research use only

IMAGES

uploads-PME101196 ANPRB His PAGE 300

Figure 1. Human ANPRB Protein, His Tag on SDS-PAGE under reducing condition.

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