| TARGET | |
|---|---|
| SYNONYMS |
AGPT2;ANG2;LMPHM10 |
| DESCRIPTION |
Recombinant Human ANGPT2(275-496) Protein with C-terminal 6×His tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
O15123 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-6×His Tag |
| MOLECULAR CHARACTERIZATION |
ANGPT2(Lys275-Phe496) 6×His tag |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 26.3 kDa after removal of the signal peptide. The apparent molecular mass of ANGPT2(275-496)-His is approximately 25-35 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome. [provided by RefSeq, Aug 2020] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME101212
Human ANGPT2(275-496) Protein, His Tag
Human ANGPT2(275-496) Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1. Human ANGPT2(275-496) Protein, His Tag on SDS-PAGE under reducing condition.
