| TARGET | |
|---|---|
| SYNONYMS |
BDA2;BMP2A;SSFSC;SSFSC1 |
| DESCRIPTION |
Recombinant Human BMP2 Protein with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
P12643 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
BMP2(Gln283-Arg396) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 39.0 kDa after removal of the signal peptide. The apparent molecular mass of BMP2-hFc is approximately 35-55 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME101216
Human BMP2 Protein, hFc Tag
Human BMP2 Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1. Human BMP2 Protein, hFc Tag on SDS-PAGE under reducing condition.
