TARGET | |
---|---|
SYNONYMS |
AZAMP;AZU;CAP37;HBP;hHBP;HUMAZUR;NAZC |
DESCRIPTION |
Recombinant Human AZU1 Protein with C-terminal 6×His tag |
DELIVERY |
In Stock |
UNIPROT ID |
P20160 |
EXPRESSION HOST |
HEK293 |
TAG |
C-6×His Tag |
MOLECULAR CHARACTERIZATION |
AZU1(Ile27-Pro248) 6×His tag |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 24.9 kDa after removal of the signal peptide. The apparent molecular mass of AZU1-His is approximately 35-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Nov 2015] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME101225
Human AZU1 Protein, His Tag
Human AZU1 Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1. Human AZU1 Protein, His Tag on SDS-PAGE under reducing condition.