TARGET | |
---|---|
SYNONYMS |
CD14 Molecule;yeloid Cell-Specific Leucine-Rich Glycoprotein;D14 Antigen;onocyte Differentiation Antigen CD14 |
DESCRIPTION |
Recombinant Human CD14(20-344) Protein with C-terminal 6×His tag |
DELIVERY |
In Stock |
UNIPROT ID |
P08571 |
EXPRESSION HOST |
HEK293 |
TAG |
C-6×His Tag |
MOLECULAR CHARACTERIZATION |
CD14(Thr20-Met344) 6×His tag |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 35.9 kDa after removal of the signal peptide. The apparent molecular mass of CD14(20-344)-His is approximately 35-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME101229
Human CD14(20-344) Protein, His Tag
Human CD14(20-344) Protein, His Tag
PRODUCT DATA
IMAGES
Figure 1.Human CD14(20-344) Protein, His Tag on SDS-PAGE under reducing condition.