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Dima Biotech

SKU(재고 관리 코드):PME101230

Human CD14(20-352) Protein, His Tag

Human CD14(20-352) Protein, His Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

CD14 Molecule;yeloid Cell-Specific Leucine-Rich Glycoprotein;D14 Antigen;onocyte Differentiation Antigen CD14

DESCRIPTION

Recombinant Human CD14(20-352) Protein with C-terminal 7×His tag

DELIVERY

In Stock

UNIPROT ID

P08571

EXPRESSION HOST

HEK293

TAG

C-7×His Tag

MOLECULAR CHARACTERIZATION

CD14(Thr20-Cys352) 7×His tag

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 36.7 kDa after removal of the signal peptide. The apparent molecular mass of CD14(20-352)-7xHis is approximately 35-55 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]

USAGE

Research use only

IMAGES

sp-PME101230 CD14 Fig.1 SDS PAGE 1
Figure 1.Human CD14(20-352) Protein, His Tag on SDS-PAGE under reducing condition.

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