TARGET | |
---|---|
SYNONYMS |
NMLY6 |
DESCRIPTION |
Recombinant Human LY6H Protein with C-terminal human Fc tag |
DELIVERY |
In Stock |
UNIPROT ID |
O94772 |
EXPRESSION HOST |
HEK293 |
TAG |
C-Human Fc Tag |
MOLECULAR CHARACTERIZATION |
LY6H(Leu26-Gly115) hFc(Glu99-Ala330) |
MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of LY6H-hFc is approximately 35-55 kDa due to glycosylation. |
PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
BACKGROUND |
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.[UniProtKB/Swiss-Prot Function] |
USAGE |
Research use only |
SKU(재고 관리 코드):PME101251
Human LY6H Protein, hFc Tag
Human LY6H Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1.Human LY6H Protein, hFc Tag on SDS-PAGE under reducing condition.