| TARGET | |
|---|---|
| SYNONYMS |
CD305;LAIR-1 |
| DESCRIPTION |
Recombinant Human LAIR1 Protein with C-terminal human Fc tag |
| DELIVERY |
In Stock |
| UNIPROT ID |
Q6GTX8 |
| EXPRESSION HOST |
HEK293 |
| TAG |
C-Human Fc Tag |
| MOLECULAR CHARACTERIZATION |
LAIR1(Gln22-His163) hFc(Glu99-Ala330) |
| MOLECULAR WEIGHT |
The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide. The apparent molecular mass of LAIR1-hFc is approximately 35-70 kDa due to glycosylation. |
| PURITY |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| FORMULATION & RECONSTITUTION |
Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| STORAGE & SHIPPING |
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| BACKGROUND |
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| USAGE |
Research use only |
Dima Biotech
SKU(재고 관리 코드):PME101252
Human LAIR1 Protein, hFc Tag
Human LAIR1 Protein, hFc Tag
PRODUCT DATA
IMAGES
Figure 1.Human LAIR1 Protein, hFc Tag on SDS-PAGE under reducing condition.
