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Dima Biotech

SKU(재고 관리 코드):PME101280

Human ECSCR Protein, hFc Tag

Human ECSCR Protein, hFc Tag

Size
Target
Uniprot ID
PRODUCT DATA
TARGET

SYNONYMS

ARIA;ECSM2

DESCRIPTION

Recombinant Human ECSCR Protein with C-terminal human Fc tag

DELIVERY

In Stock

UNIPROT ID

Q19T08

EXPRESSION HOST

HEK293

TAG

C-Human Fc Tag

MOLECULAR CHARACTERIZATION

ECSCR(Gln25-Val122) hFc(Glu99-Ala330)

MOLECULAR WEIGHT

The protein has a predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of ECSCR-hFc is approximately 35-70 kDa due to glycosylation.

PURITY

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

FORMULATION & RECONSTITUTION

Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

STORAGE & SHIPPING

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

BACKGROUND

The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

USAGE

Research use only

IMAGES

sp-PME101280 ECSCR Fig.1 SDS PAGE 1
Figure 1.Human ECSCR Protein, hFc Tag on SDS-PAGE under reducing condition.

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