Myosin VIIa polyclonal antibody

Myosins are molecular motors that move along filamentous Actin and influence cellular movements such as phagocytosis. There are seven classes of myosins in vertebrates, including Myosin II, and six unconventional Myosin classes, designated I, V, VI, VII, IX and X. Myosin VIIa is a plus end-directed motor that influences cilia formation and cell adhesion. Mutations in the human Myosin VIIa gene correlate with Usher syndrome, a disease characterized by congenital sensorineural deafness, vestibular dysfunction and retinitis pigmentosa.