BMS1 polyclonal antibody

BMS1 (Ribosome biogenesis protein BMS1 homolog) is a 1,282 amino acid protein encoded by the human gene BMS1. BMS1 is a nuclear protein that belongs to the BMS1/TSR1 family (BMS1 subfamily). BMS1 is believed to act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus. The 40S ribosomal subunit is an important member of the 80S ribosome complex, which also includes initiator tRNA and a 60S ribosomal subunit. The 80S ribosome is assembled by eukaryotic initiation factors (eIFs) at the initiation codon of mRNA in order to begin translation initiation. The joining of these ribosomal subunits requires eIF5B.