NDUFB7 polyclonal antibody

Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUB7 (NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7), also known as NADH-ubiquinone oxioreductase B18 subunit, complex I-B18 (CI-B18) or cell adhesion protein SQM1, is a 137 amino acid accessory subunit of complex 1. Ubiquitously expressed, NDUFB7 localizes to the mitochondrial inner membrane on the matrix side. NDUFB7 contains a sevenfold repeat of positively-charged residues that may indicate a role in protein-protein interactions.